Journal of Environmental Pathology, Toxicology and Oncology

ISSN for PRINT: 0731-8898

For Online Access

Best Paper Award Selection - Editorial Board Site

2008, Volume27

Issue 1

77 pages

Issue price - $202.00

Seth A. Gross
Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, MN, USA

Herbert C. Wolfsen
Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA

This is a review of the uses, history, and current status of photodynamic therapy for diseases of the esophagus, specifically Barrett's dysplasia and early esophageal carcinoma. This paper describes the clinical experience of photodynamic therapy and compares the use of various photosensitizer drugs. Finally, important biophotonics developments are discussed, including their anticipated impact for improved endoscopic detection of dysplasia and carcinoma. In addition, methods for real-time photodynamic therapy and light dosimetry are provided in order to optimize ablation treatment outcomes while minimizing the risk of complications.

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