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Journal of Environmental Pathology, Toxicology and Oncology

 

ISSN for PRINT: 0731-8898

Institutional price:

$672.00

Issues per year:

4

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2002, Volume21

Issue 4

  80 pages  

   

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Issue price - $160.00  

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  • Escape Mechanisms in Tumor Immunity: An Update
  • Ludmila Muller
    Tubingen Aging and Tumour Immunology Group (TATI), Section for Transplantation Immunology, Medizinische

    Rolf Kiessling
    Department of Oncology-Pathology, Karolinska Institutet, S-17176 Stockholm, Sweden

    Robert C. Rees
    Department of Life Sciences, Faculty of Science and Mathematics, The Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, England

    Graham Pawelec
    Tubingen Aging and Tumour Immunology Group (TATI), Section for Transplantation Immunology, Medizinische


    ABSTRACT

    Evidence that tumors are immunogenic continues to accumulate. Although they frequently do express antigens in a form recognizable by the host immune system, tumors commonly “escape” the immune response. Tumors may therefore progress by evolving variants that can evade immune responses or by developing other strategies to avoid immune control. The purpose of this review is to consider the current status of knowledge concerning these different tumor-escape strategies, in the form of an update of previous publications in this journal.

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