Journal of Long-Term Effects of Medical Implants

ISSN for PRINT: 1050-6934

For Online Access

Best Paper Award Selection - Editorial Board Site

2007, Volume17

Issue 2

119 pages

Issue price - $189.00

Laura Quigley
Department of Clinical Epidemiology & Biostatistics, McMaster University,Hamilton, Ontario, Canada

Sheila Sprague
Department of Clinical Epidemiology & Biostatistics,McMaster University, Hamilton, Ontario, Canada

Brad Petrisor
Department of Clinical Epidemiology & Biostatistics, McMaster University,Hamilton, Ontario, Canada

Mohit Bhandari
Division of Orthopaedic Trauma, Hamilton Health Sciences, General Hospital Site, 237 Barton Street East, Hamilton, Ontario L8L 2X2 Canada

Meta-analyses can be an excellent method to summarize the existing literature of studies concerning orthopaedic implants and devices. It is important to understand how meta-analyses are conducted and to be able to evaluate whether a meta-analysis has strong methodological rigor to help with clinical decisions. This paper begins with an overview of what a meta-analysis is and why it is useful. The second section provides the important characteristics of conducting a meta-analysis. The third section will provide detail of how to interpret a meta-analysis, including topics such as the quality of the included studies, comparing the results between studies, pooling data, and how to interpret the results. The benefits and limitations are presented, along with recommendations of how to ensure future high-quality meta-analyses. Meta-analyses are useful for synthesizing the results of multiple primary studies and can provide excellent evidence for clinical decisions; however, it is important that methodological flaws are limited.

Download article, 121-133 pages

Article price - $35.00

<< Previous article   Next article >>