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Journal of Long-Term Effects of Medical Implants

 

ISSN for PRINT: 1050-6934

Institutional price:

$1021.00

Issues per year:

6

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2004, Volume14

Issue 3

  105 pages  

DOI: 10.1615/JLongTermEffMedImplants.v14.i3   

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  • Obstructive Sleep Apnea: Part I. Pathophysiology, Diagnosis, and Medical Management
  • James J. Carswell, MD
    Division of Pulmonary Medicine, University of Virginia Health System, Charlottesville, Virginia, USA

    Steven M. Koenig, MD
    Division of Pulmonary Medicine, University of Virginia Health System, Charlottesville, Virginia, USA


    ABSTRACT

    Obstructive sleep disordered breathing (OSDB) is a spectrum of disease resulting from changes in the upper airway. It affects a large proportion of the adult population, and in its most severe form, obstructive sleep apnea syndrome (OSAS), patients suffer the adverse effects of sleep disturbance and oxygen desaturation. Daytime somnolence leads to a significantly higher incidence of automobile and work-related accidents, while nocturnal hy-poxia is associated with multiple physiological derangements. Patients with OSAS have higher incidences of hypertension, coronary artery disease, congestive heart failure, and arrhythmias. Noninvasive testing is used to confirm the diagnosis, and treatment may be conservative, medical, or surgical. Treatment is designed to improve daytime somnolence and has been shown to improve morbidity and mortality among patients with OSDB.

    DOI: 10.1615/JLongTermEffMedImplants.v14.i3.20

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