Critical Reviews™ in Immunology

ISSN for PRINT: 1040-8401

For Online Access

Best Paper Award Selection - Editorial Board Site

2007, Volume27

Issue 2

124 pages

Issue price - $153.00

Marilia Cascalho
Transplantation Biology and the Departments of Immunology, Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN

Jeffrey L. Platt
Transplantation Biology and the Departments of Immunology, Surgery, and Pediatrics, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN

T cells clearly help B cells to produce antibodies and acquire memory. Recently, B cells were found to support some T-cell responses through antigen presentation, and perhaps more importantly, through the generation of diverse T cells and lymphoid organogenesis. These new findings show that the development and function of T cells depend on B cells independently of specific antibody production.

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