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Critical Reviews™ in Oncogenesis

 

ISSN for PRINT: 0893-9675

Institutional price:

$632.00

Issues per year:

4

For Online Access

Best Paper Award Selection - Editorial Board Site

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2006, Volume12

Issue 3-4

  140 pages  

   

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  • Emerging Technologies for Genome-wide DNA Methylation Profiling in Cancer
  • Izuho Hatada
    Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi 371-8511 Japan


    ABSTRACT

    Genome-wide epigenetics, namely, epigenomics, is one of the current frontiers in cancer genomics. Epigenetic silencing of tumor-suppressor genes plays an important role in the pathogenesis of most cancers. Several technologies are emerging for the genome-wide profiling of DNA methylation to find new tumor-suppressor genes and predictions for clinical phenotypes in individual patients.

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