Published 4 issues per year
ISSN Print: 0893-9675
ISSN Online: 2162-6448
Indexed in
Positive and Negative Regulation by NK Cells in Cancer
ABSTRACT
Our understanding of NK biology has expanded immensely since the initial discovery of natural killer cells in 1975. New studies have uncovered various levels of immune regulation both on and by unique subsets of NK cells, which go well beyond simple receptor−ligand interactions between NK cells and target cancer cells. Distinct suppressor and effector populations of NK cells have been delineated in both viral and tumor models. Interactions between NK cells and dendritic cells, T cells, and B cells also dramatically alter the overall immune response to cancer. To exploit the diverse functional abilities of NK cell subsets for cancer immunotherapies, it is important to understand NK cell biology and NK regulator mechanisms.
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Mace Thomas A., Ware Michael B., King Samantha A., Loftus Shannon, Farren Matthew R., McMichael Elizabeth, Scoville Steven, Geraghty Connor, Young Gregory, Carson William E., Clinton Steven K., Lesinski Gregory B., Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function, Scientific Reports, 9, 1, 2019. Crossref
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Antohe Mihaela, Nedelcu Roxana, Nichita Luciana, Popp Cristiana, Cioplea Mirela, Brinzea Alice, Hodorogea Anastasia, Calinescu Andreea, Balaban Mihaela, Ion Daniela, Diaconu Carmen, Bleotu Coralia, Pirici Daniel, Zurac Sabina, Turcu Gabriela, Tumor infiltrating lymphocytes: The regulator of melanoma evolution (Review), Oncology Letters, 2019. Crossref
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Sorrentino Carlo, D’Antonio Luigi, Fieni Cristiano, Ciummo Stefania Livia, Di Carlo Emma, Colorectal Cancer-Associated Immune Exhaustion Involves T and B Lymphocytes and Conventional NK Cells and Correlates With a Shorter Overall Survival, Frontiers in Immunology, 12, 2021. Crossref
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Wu Ming, Wang Sheng, Chen Jian-Yu, Zhou Li-Juan, Guo Zi-Wen, Li Yu-Hua, Therapeutic cancer vaccine therapy for acute myeloid leukemia, Immunotherapy, 13, 10, 2021. Crossref
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Aguilar Ethan G., Dunai Cordelia, Judge Sean J., Zamora Anthony E., Khuat Lam T., Vick Logan V., Collins Craig P., Stoffel Kevin M., Alvarez Maite, Barao Isabel, Miller Jeffrey S., Blazar Bruce R., Chevallier Patrice, Retiere Christelle, Canter Robert J., Murphy William J., Activation status dictates the function of unlicensed natural killer cells in mice and humans, Blood Advances, 5, 20, 2021. Crossref
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Fares Jawad, Gupta Sumit, Gopalakrishnan Vidya, Khatua Soumen, NK cells in brain tumors: From biology to treatment, in Successes and Challenges of NK Immunotherapy, 2021. Crossref
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Allison Michaela, Mathews Joel, Gilliland Taylor, Mathew Stephen O., Natural Killer Cell-Mediated Immunotherapy for Leukemia, Cancers, 14, 3, 2022. Crossref
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Venglar Ondrej, Bago Julio Rodriguez, Motais Benjamin, Hajek Roman, Jelinek Tomas, Natural Killer Cells in the Malignant Niche of Multiple Myeloma, Frontiers in Immunology, 12, 2022. Crossref
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Lorenzo-Anota Helen Y., Martínez-Loria Alan B., Tamez-Guerra Reyes S., Scott-Algara Daniel, Martínez-Torres Ana C., Rodríguez-Padilla Cristina, Changes in the natural killer cell repertoire and function induced by the cancer immune adjuvant candidate IMMUNEPOTENT-CRP, Cellular Immunology, 374, 2022. Crossref
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Sharrock Jessica, Natural Killer Cells and Their Role in Immunity, EMJ Allergy & Immunology, 2019. Crossref
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Lu Yihua, Xiao J., He Y., Natural Killer (NK) cells in immunotherapy and perspectives in antitumour approaches, BIO Web of Conferences, 55, 2022. Crossref
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