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ISSN for PRINT: 1521-9437
Institutional price: |
$538.00 |
Issues per year: |
4 |
2006, Volume8
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98 pages |
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Issue price - $138.00
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Moderate Angiotensin I Converting Enzyme (ACE) Inhibitors from the Edible Mushroom Pleurotus citrinopileatus Singer (Agaricomycetideae)
Hiroyuki
Suzuki
Laboratory of Bioresource Science, Department of Applied and Environmental Chemistry, Kitami Institute of Technology, Kitami 090-8507, Japan
Masaaki
Kiyoto
Laboratory of Bioresource Science, Department of Applied and Environmental Chemistry, Kitami Institute of Technology, Kitami 090-8507, Japan
Naoki
Nobuyama
Laboratory of Bioresource Science, Department of Applied and Environmental Chemistry, Kitami Institute of Technology, Kitami 090-8507, Japan
Takaaki
Hara
Hakuju Life Science Co., Ltd., 32-17 Oyamahigashi-cho, Itabashi-ku, Tokyo 173-0004, Japan
Yuzo
Yagi
Hakuju Life Science Co., Ltd., 32-17 Oyamahigashi-cho, Itabashi-ku, Tokyo 173-0004, Japan
Iwao
Togashi
Department of Material Chemistry, Asahikawa National College of Technology, Asahikawa 071-8142, Japan
Akira
Harada
Chemical Biology Institute, Inc., 4-9-2-1Utsukushigaoka, Kiyota-ku, Sapporo 004-0814, Japan
Masakazu
Aoyama
Laboratory of Bioresource Science, Department of Applied and Environmental Chemistry, Kitami Institute of Technology, Kitami 090-8507, Japan
ABSTRACT
The acetone extract of Pleurotus citrinopileatus showed a moderate inhibitory activity against the angiotensin I converting enzyme (ACE). The 50% inhibitory concentration (IC50) of the extract for ACE activity was 50.2 mg ml−1. D-mannitol was isolated as an active principle with a yield of 5.75 %. The IC50 value of the compound was 33.4 mg ml−1. D-arabitol and glycerol were also detected in the acetone extract. D-arabitol acted as an ACE inhibitor, whereas only limited activity was observed by the dose of glycerol.
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Article price - $35.00 |
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