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International Journal of Medicinal Mushrooms

 

ISSN for PRINT: 1521-9437

Institutional price:

$538.00

Issues per year:

4

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Best Paper Award Selection - Editorial Board Site

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2001, Volume3

Issue 1

  76 pages  

   

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Issue price - $128.00  

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  • Hypoglycemic Effects of Mycelia Produced from a Submerged Culture of Phellinus linteus (Berk. et Curt.) Teng (Aphyllophoromycetideae) in Streptozotocin-lnduced Diabetic Rats
  • Dong-Hyun Kim
    department of Biotechnology, Taegu University, Kyungbuk 712-714, South Korea

    Byung-Kun Yang
    department of Biotechnology, Taegu University, Kyungbuk 712-714, South Korea

    Nam-Jung Hur
    department of Biotechnology, Taegu University, Kyungbuk 712-714, South Korea

    Surajit Das
    department of Biotechnology, Taegu University, Kyungbuk 712-714, South Korea

    Jong-Won Yun
    department of Biotechnology, Taegu University, Kyungbuk 712-714, South Korea

    Young-Sun Choi
    department of Food and Nutrition, Taegu University, Kyungbuk 712-714, South Korea

    Chi-Hyun Song
    Department of Biotechnology, Taegu University, Kyungbuk 712-714, South Korea


    ABSTRACT

    The hypoglycemic effect of Phellinus linteus (Berk. et Curt.) Teng dried mycelia was investigated in streptozotocin-induced diabetic rats. It proved to have efficacy in lowering substantially the plasma glucose and total triglyceride (TG) level in diabetic rats. A mycelial dose of 5-10% proved almost equally effective in lowering the plasma glucose level as much as 28%. It also caused a dramatic decrease in TG level at a dose of 5.0%. It lowered the TG level (56.3%) of the diabetic rats, which is even below that of normal controls. The values of glutamic pyruvic transaminase and glutamic oxaloacetic transaminase in plasma were also estimated and exhibited a substantial reduction in activity after the administration of dried mycelia. The result obtained in the present investigation indicated the efficacy of P. linteus dried mycelial powder as a therapeutic regimen for the control of diabetics.

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