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International Journal of Medicinal Mushrooms

 

ISSN for PRINT: 1521-9437

Institutional price:

$538.00

Issues per year:

4

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Best Paper Award Selection - Editorial Board Site

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2003, Volume5

Issue 3

  112 pages  

DOI: 10.1615/InterJMedicMush.v5.i3   

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  • The Role of Polysaccharides Derived from Medicinal Mushrooms in Cancer Treatment Programs: Current Perspectives (Review)
  • John E. Smith
    Department of Bioscience&Biotechnology University of Strathclyde Royal College, Building 204 George Street Glasglow, Scotland, UK; and Mycobiotech Pte Ltd., Singapore Science Part, Singapore

    Richard Sullivan
    Head of Clinical Programmes, Cancer Research UK, PO Box 123, Lincoln’s Inn Field, London WC2A 3PX, UK

    Neil J. Rowan
    Department of Bioscience and Biotechnology, University of Strathclyde, 204 George Street, Glasgow G1 1XW, Scotland, UK


    ABSTRACT

    Mushroom-derived polysaccharides are now considered to be compounds that are able to modulate animal and human immune responses and to inhibit certain tumor growths. This review sets out the current information on the use of various mushroom polysaccharides in cancer treatments. Many human cancer cell lines have been studied, and in some cases direct cytotoxic effects have been demonstrated. Several mushroom polysaccharide compounds have proceeded through Phases I, II, and III clinical trials and are used extensively and successfully in Asia to treat various cancers. It is considered that such proprietary mushroom compounds will be seen mainly as complementary or adjunctive therapies to be used together with mainstream care therapies.

    DOI: 10.1615/InterJMedicMush.v5.i3.10

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