International Journal of Medicinal Mushrooms

ISSN for PRINT: 1521-9437

For Online Access

Best Paper Award Selection - Editorial Board Site

2003, Volume5

Issue 3

112 pages

DOI: 10.1615/InterJMedicMush.v5.i3

Issue price - $128.00

Chunhui Fang
Department of Pharmacology, Peking University Health Science Center, Peking, R. P. China

Zhi-Bin Lin
Department of Pharmacology, School of Basic Medical Sciences, Beijing University, Beijing 100083, P. R. China

The effects of Agaricus brasiliensis extract (ABE) on the functions of lymphocytes of a mouse spleen in vitro were investigated. Mouse spleen lymphocyte proliferation induced by ConA was assessed using both normal lymphocytes and lymphocytes inhibited by cyclosporin A or hydrocortisone. Mixed lymphocyte reaction (MLR) was conducted with lymphocytes preincubated with mitomycin C and normal lymphocytes from C57BL/6j mice. ABE (5 ~ 100 μg/mL) can enhance the proliferation of mouse lymphocytes stimulated by ConA in vitro and can partially restore the response of inhibited lymphocytes to ConA within 5 ~ 50 μg/mL. ABE (10 ~ 500 μg/mL) can also enhance mixed lymphocyte reaction. ABE can enhance the immune functions of lymphocyte in vitro.

DOI: 10.1615/InterJMedicMush.v5.i3.60 Download article, 6 pages

Article price - $35.00

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