Critical Reviews™ in Neurobiology

ISSN for PRINT: 0892-0915

For Online Access

Best Paper Award Selection - Editorial Board Site

2000, Volume14

Issue 2

80 pages

Issue price - $110.00

Charles W. Bradberry
Departments of Psychiatry and Laboratory Medicine, Yale University School of Medicine, West Haven, CT 06516

This review provides a comprehensive summary of the use of microdialysis procedures in nonhuman primates. Using these methods in primates is feasible, including both the anesthetized and awake preparations. The latter permit neurochemical sampling during complex information processing and behavioral performance. The close homology in structure and function between human and nonhuman primate brain makes using nonhuman primates particularly appealing, and the literature suggests that their use has provided instances of unique insight into brain structure and function. The continued use of these methods in areas such as the neurobiology of addiction, affective disorders, and psychosis will help in our ever-increasing understanding of the complex pathophysiologies of these disorders.

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