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Critical Reviews™ in Neurobiology

ISSN for PRINT: 0892-0915

Institutional price:	$649.00
Issues per year:	4

Best Paper Award Selection - Editorial Board Site

2006, Volume18

209 pages

Issue price - $338.00

Homeostatic Plasticity: Comparing and Contrasting Cortical and Hippocampal Studies. A Review

Eric Leininger
Department of Cell and Molecular Biology, Tulane University, New Orleans, LA, USA

Andrei B. Belousov
Department of Molecular and Integrative Physiology, The University of Kansas Medical Center, Kansas City, KS, USA

ABSTRACT

Homeostatic plasticity is an important physiological process in the mammalian nervous system. In this review, we discuss methodological and mechanistic similarities and differences in cortical and hippocampal studies of homeostatic plasticity. Although there are many similarities, there are also region-specific differences in the effects and/or mechanisms that regulate homeostatic plasticity in these two regions. In this review, we propose a new experimental paradigm to study homeostatic plasticity that may address some unanswered questions in the field.