Critical Reviews^TM in Neurobiology encompasses a wide range of disciplines including experimental neurobiology and electrophysiology. Recent developments in analytical instrumentation and quantitative disciplines have contributed to the advancement of the field. Consequently, its relevance in modern medicine is of paramount importance in developing new diagnostic methods.
Critical Reviews^TM in Neurobiology publishes reviews and significant contributions from a wide range of areas related to neurobiology in the context of their impact on important clinical problems. The journal presents up-to-date information from basic neuroscience, clinical neurobiology, neurosurgery and psychiatry. Pertinent issues from developmental neurobiology, memory, cognition, geriatrics and neuroimmunology will also be examined. High quality review papers which integrate basic neuroscience and clinical neurology are invited.

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Hippocampal Long-Term Synaptic Plasticity and Signal Amplification of NMDA Receptors
John F. MacDonald, Michael F. Jackson, Michael A. Beazely

On the Use of Neuro-2a Neuroblastoma Cells Versus Intact Neurons in Primary Culture for Neurotoxicity Studies
Keith T. LePage, Robert W. Dickey, William H. Gerwick, Edward L. Jester, Thomas F. Murray

Regulation of Cannabinoid CB1 Receptors in the Central Nervous System by Chronic Cannabinoids
Laura J. Sim-Selley

Social Deprivation of Neonatal, Adolescent, and Adult Rats Has Distinct Neurochemical and Behavioral Consequences
F. Scott Hall

Endocannabinoid Signaling and Synaptic Plasticity in the Brain
Ping Jun Zhu

Cognitive Impairment in Schizophrenia Is the Core of the Disorder
Brita Elvevag, Terry E. Goldberg