In a previous paper, a kind of solid oxide fuel cell combined cycle-SOFC power generation system with chemical looping combustor (CL-FCCC) has been studied. This cycle is made up of chemical looping combustor, solid oxide fuel cell, intercooling compressors, gas turbine, steam turbine, HRSG, and other auxiliary facilities. The key difference between other SOFC power systems and this one is the adoption of chemical looping combustor which can help to increase system's average temperature and pressure while provides energy for fuel and air preheating in the same time. But this configuration might not be the best one. So an optimization both of flowsheet and parameters was initiated in order to improve the performance of CL-FCCC. Both optimal flowsheet and fundamental parameters can be obtained by doing non-linear optimization of a more comprehensive system. The results achieved up to now are presented in the following.