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Critical Reviews™ in Eukaryotic Gene Expression
Facteur d'impact: 2.156 Facteur d'impact sur 5 ans: 2.255 SJR: 0.649 SNIP: 0.599 CiteScore™: 3

ISSN Imprimer: 1045-4403
ISSN En ligne: 2162-6502

Critical Reviews™ in Eukaryotic Gene Expression

Executive Editors: Gary Stein, Janet L. Stein, Jane B. Lian

Managing Editor: Christine Rogers

Objectifs et champs d'application

Critical ReviewsTM in Eukaryotic Gene Expression presents timely concepts and experimental approaches that are contributing to rapid advances in our mechanistic understanding of gene regulation, organization, and structure within the contexts of biological control and the diagnosis/treatment of disease. The journal provides in-depth critical reviews, on well-defined topics of immediate interest, written by recognized specialists in the field. Extensive literature citations provide a comprehensive information resource.
Reviews are developed from an historical perspective and suggest directions that can be anticipated. Strengths as well as limitations of methodologies and experimental strategies are considered. The contributions of molecular, cellular, biochemical, genetic, genomic, and proteomic approaches to eukaryotic gene expression are incorporated into reviews. The relationship between gene structure and function is stressed, with emphasis on coordinate control of biological processes. Regulatory mechanisms are explored from the perspective of sequences and regulatory molecules that influence structure and expression of eukaryotic genes as well as in relation to cellular architecture and its relationship to development of cell specialization and tissue organization. Processes that include genetic and epigenetic control, cell cycle regulation, differentiation, transformation and tumorigenesis, senescence, cell survival and apoptosis, development, reproduction, cell fate, lineage commitment, stem cell biology and regenerative medicine are covered.
All articles are by invitation; however, the editors welcome suggestions of both topics and authors.

La plupart des articles téléchargés

Mini-Review: The Non-Immune Functions of Toll-Like Receptors
Ying Song, Li Meng Shou, Li-Yao Ai, Yun Bei, Man-Ting Chen

Diagnostic, Prognostic, and Therapeutic Potencies of Circulating miRNAs in Acute Myocardial Infarction
Farshad Mirzavi, Safieh Ebrahimi, Kiarash Ghazvini, Seyed Mahdi Hassanian Mehr, Seyed Isaac Hashemy

Is Cannabidiol a Promising Substance for New Drug Development? A Review of its Potential Therapeutic Applications
Nida Noreen, Faqir Muhammad, Bushra Akhtar, Farooq Azam, Muhammad Irfan Anwar

Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stem Cells: Characterization, Differentiation, and Applications in Cartilage Tissue Engineering
Xu Li, Mingjie Wang, Xiaoguang Jing, Weimin Guo, Chunxiang Hao, Yu Zhang, Shuang Gao, Mingxue Chen, Zengzeng Zhang, Xueliang Zhang, Shi Shen, Bin Zhang, Hai Xian, Zehao Wang, Yu Wang, Xiang Sui, Aiyuan Wang, Jiang Peng, Shibi Lu, Shuyun Liu, Quanyi Guo

Tumor Necrosis Factor-α Signaling in Macrophages
Narayanan Parameswaran, Sonika Patial

Wnt Network: A Brief Review of Pathways and Multifunctional Components
Fereshte Abdolmaleki, Hossein Ahmadpour-Yazdi, Seyed Mohammad Gheibi Hayat, Nematollah Gheibi, Thomas P. Johnston, Amirhossein Sahebkar