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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Activity of Aqueous Extracts of Lion's Mane Mushroom Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae) on the Neural Cell Line NG108-15

Volume 9, Issue 1, 2007, pp. 57-65
DOI: 10.1615/IntJMedMushr.v9.i1.70
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ABSTRACT

The pharmacology and clinical applications of medicinal mushrooms have been extensively documented. One such mushroom, Hericium erinaceus, has been reported to reduce gastric ulcers and the aftereffects of chemotherapy. H. erinaceus is a temperate mushroom but is now being cultivated in tropical Malaysia. In this study, we investigated the activity of aqueous extracts of fruit bodies and mycelium of H. erinaceus in stimulating neurite outgrowth from cultured cells of the neural hybrid clone NG108-15 with a long-term view toward the possible use of this mushroom in the treatment of neurological disorders. Our results showed that extracts of H. erinaceus grown in tropical conditions do induce neurite outgrowth from these cells. Maximum stimulation of neurite outgrowth was recorded with mycelial extracts, and the least stimulation was observed with oven-dried fruit body extract. Aqueous extracts of H. erinaceus therefore contain neuroactive compounds that stimulate neurite outgrowth in vitro.

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  2. Wong Kah-Hui, Naidu Murali, David Pamela, Abdulla Mahmood Ameen, Abdullah Noorlidah, Kuppusamy Umah Rani, Sabaratnam Vikineswary, Peripheral Nerve Regeneration Following Crush Injury to Rat Peroneal Nerve by Aqueous Extract of Medicinal MushroomHericium erinaceus(Bull.: Fr) Pers. (Aphyllophoromycetideae), Evidence-Based Complementary and Alternative Medicine, 2011, 2011. Crossref

  3. Wong Jing-Yang, Abdulla Mahmood Ameen, Raman Jegadeesh, Phan Chia-Wei, Kuppusamy Umah Rani, Golbabapour Shahram, Sabaratnam Vikineswary, Gastroprotective Effects of Lion’s Mane MushroomHericium erinaceus(Bull.:Fr.) Pers. (Aphyllophoromycetideae) Extract against Ethanol-Induced Ulcer in Rats, Evidence-Based Complementary and Alternative Medicine, 2013, 2013. Crossref

  4. Wong Kah-Hui, Kanagasabapathy Gowri, Naidu Murali, David Pamela, Sabaratnam Vikineswary, Hericium erinaceus (Bull.: Fr.) Pers., a medicinal mushroom, activates peripheral nerve regeneration, Chinese Journal of Integrative Medicine, 22, 10, 2016. Crossref

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  7. Jiang Shengjuan, Wang Songhua, Sun Yujun, Zhang Qiang, Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals, Applied Microbiology and Biotechnology, 98, 18, 2014. Crossref

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  12. Kim Young Ock, Lee Sang Won, Kim Jin Seong, A comprehensive review of the therapeutic effects of Hericium erinaceus in neurodegenerative disease, Journal of Mushroom, 12, 2, 2014. Crossref

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  17. Diling Chen, Tianqiao Yong, Jian Yang, Chaoqun Zheng, Ou Shuai, Yizhen Xie, Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus, Frontiers in Pharmacology, 8, 2017. Crossref

  18. Sabaratnam Vikineswary, Phan Chia-Wei, Neuroactive Components of Culinary and Medicinal Mushrooms With Potential to Mitigate Age-Related Neurodegenerative Diseases, in Discovery and Development of Neuroprotective Agents from Natural Products, 2018. Crossref

  19. He Jinzhe, Fan Peng, Feng Simin, Shao Ping, Sun Peilong, Isolation and Purification of Two Isoflavones from Hericium erinaceum Mycelium by High-Speed Counter-Current Chromatography, Molecules, 23, 3, 2018. Crossref

  20. WONG Kah-Hui, KANAGASABAPATHY Gowri, BAKAR Robiah, PHAN Chia-Wei, SABARATNAM Vikineswary, Restoration of sensory dysfunction following peripheral nerve injury by the polysaccharide from culinary and medicinal mushroom, Hericium erinaceus (Bull.: Fr.) Pers. through its neuroregenerative action, Food Science and Technology, 35, 4, 2015. Crossref

  21. Pang Jun-Rui, Goh Veronica Ming-Jun, Tan Cheng-Yau, Phang Siew-Moi, Wong Kah-Hui, Yow Yoon-Yen, Neuritogenic and in vitro antioxidant activities of Malaysian Gracilaria manilaensis Yamamoto & Trono, Journal of Applied Phycology, 30, 6, 2018. Crossref

  22. LEW Sze-Yuen, YOW Yoon-Yen, LIM Lee-Wei, WONG Kah-Hui, Antioxidant-mediated protective role of Hericium erinaceus (Bull.: Fr.) Pers. against oxidative damage in fibroblasts from Friedreich’s ataxia patient, Food Science and Technology, 40, suppl 1, 2020. Crossref

  23. Xiong Chuan, Luo Qiang, Huang Wen-Li, Li Qiang, Chen Cheng, Chen Zu-Qin, Yang Zhi-Rong, The potential neuritogenic activity of aqueous extracts from Morchella importuna in rat pheochromocytoma cells, Food Science and Biotechnology, 26, 6, 2017. Crossref

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  26. John Priscilla A., Wong Kah - Hui, Naidu Murali, Sabaratnam Vikineswary, David Pamela, Combination Effects of Curcumin and Aqueous Extract of Lignosus rhinocerotis Mycelium on Neurite Outgrowth Stimulation Activity in PC-12 Cells, Natural Product Communications, 8, 6, 2013. Crossref

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  28. Badalyan Susanna M., Rapior Sylvie, The Neurotrophic and Neuroprotective Potential of Macrofungi, in Medicinal Herbs and Fungi, 2021. Crossref

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