Critical Reviews™ in Immunology
Immunology covers a broad spectrum of investigations at the genes, molecular, cellular, organ and system levels to reveal defense mechanisms against pathogens as well as protection against tumors and autoimmune diseases. The great advances in immunology in recent years make this field one of the most dynamic and rapidly growing in medical sciences. Critical ReviewsTM in Immunology (CRI) seeks to present a balanced overview of contemporary adaptive and innate immune responses related to autoimmunity, tumor, microbe, transplantation, neuroimmunology, immune regulation and immunotherapy from basic to translational aspects in health and disease. The articles that appear in CRI are mostly obtained by invitations to active investigators. But the journal will also consider proposals from the scientific community. Interested investigators should send their inquiries to the editor before submitting a manuscript.
Review Articles: The journal publishes critical and timely review articles in various aspects of contemporary immunology and it is hoped that the articles will provide a critical analysis rather than a passive account of information in a given topic. The articles are rigorously refereed by outstanding and expert investigators. Review articles are, mostly, by invitation and unsolicited papers cannot be considered. However, proposals for reviews are encouraged and will be seriously considered by the Editorial Board. A proposal should give a short description (about one page) of the intended work. There are no page charges for publication.
To allow constructive discussion among immunologists and to maximize exchange of ideas the journal will publish (in addition to the review articles) the following:
Opinions/Hypotheses: These are proposed concepts/hypotheses, based on sound experimental data available in the scientific literature or based on the author's outline of work that could be tested experimentally. Opinions and hypotheses are subject to the usual peer review process.
Letters to the Editor: These could be responses to hypotheses, clarifications, viewpoints, and other such matters that will encourage discussion. This is an open forum. The letters, however, should be scholarly, and personal attacks or abusive style will not be permitted. Letters to the editor will be peer reviewed.
News and Comments: These include important news items such as major breakthroughs and new discoveries in immunology and even other biological sciences that might have an impact on the field of immunology. Summaries of national and international meetings are also appropriate news items. News and comments will also be peer reviewed.
Book Reviews and Books Received: Authors and publishers of immunology books are invited to submit their books for review and evaluation by the journal. Usually, one or two reviews can be assigned to a given issue. However, as a service to the scientific community, all books that are received will be listed.
Calendar of Events: As a service to the scientific community, the journal will list titles and dates of immunology meeting up to one year in advance. Organizers of future meetings are encouraged to submit title, date, location, and name/address/telephone number of the person to contact for further information. There will be no charge for this service.
M1 and M2 Macrophages: Oracles of Health and Disease
LPS-induced Cytokine Production in Human Monocytes and Macrophages
Manuela Rossol, Holger Heine, Undine Meusch, Dagmar Quandt, Carina Klein, Matthew J. Sweet, Sunna Hauschildt
Lymphocyte Activation in Health and Disease
Michael J. Berridge
Mechanical Cues for T Cell Activation: Role of Piezo1 Mechanosensors
Chinky Shiu Chen Liu, Dipyaman Ganguly
T Cell Receptors for Gene Transfer in Adoptive T Cell Therapy
Preeti Sharma, David M. Kranz
The Nature of Selection on the Major Histocompatibility Complex
Victor Apanius, Dustin Penn, Patricia R. Slev, L. Ramelle Ruff, Wayne K. Potts