An experimental work was conducted to investigate the pressure drops & friction factors for liquid of R134a and R12 through the micro-channels with triangular and rectangular cross sections. The equivalent diameters were 0.6mm and 0.4mm. The test section was different from the one before. The friction factors for liquid flow of refrigerant R-134a and R-12 were measured. Results show the correlation of the friction factors can be expressed as a formula f=c/Rem. But the influence of roughness can't be neglected in the comparison. The third series of specimen were designed and manufactured in accordance with the experience before.